The Retro-Suzuki Reaction? A Palladium-Catalyzed Carbon-Carbon Decoupling of (Hetero)Biaryls

We report the development of a novel C-C decoupling reaction mediated by a palladium/bis(phosphine) catalyst system. This methodology is the first of its kind, and allows for the chemoselective scission of Ar-Ar bonds to give aryl halides and arylboronic esters.